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Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity

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The advantages of GLP-1 agonists include substantial clinical trial data supporting their efficacy and safety, FDA approval for weight management in certain populations, proven results with many users losing 15-20% or more of body weight, and effects on appetite that make caloric restriction feel natural

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Such modulatory effects on cholesterol levels hint at its broader applicability, beyond just weight reduction, perhaps in the realm of metabolic health optimization [Usman et al., 2022]

My dad was diabetic and injected subcutaneously, alternating between tummy and thighs